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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX58
All Species:
31.82
Human Site:
Y258
Identified Species:
70
UniProt:
Q96C10
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C10
NP_077024.2
678
76613
Y258
R
K
F
G
T
Q
M
Y
E
Q
Q
V
V
K
L
Chimpanzee
Pan troglodytes
XP_001167051
678
76609
Y258
R
N
F
G
T
Q
M
Y
E
Q
Q
V
V
K
L
Rhesus Macaque
Macaca mulatta
XP_001108799
678
76729
Y258
R
N
F
G
T
Q
M
Y
E
Q
Q
V
V
K
L
Dog
Lupus familis
XP_850033
678
76952
Y258
R
D
F
G
T
Q
T
Y
E
Q
Q
V
V
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99J87
678
76708
Y258
Q
Q
F
G
T
Q
M
Y
E
Q
Q
V
V
Q
L
Rat
Rattus norvegicus
NP_001092258
678
76894
Y258
Q
Q
F
G
T
Q
M
Y
E
Q
Q
V
V
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
I504
W
I
V
N
I
Q
K
I
C
K
V
F
Q
I
P
Chicken
Gallus gallus
XP_422031
1285
144686
Y854
S
E
F
G
S
Q
P
Y
E
Q
W
V
I
R
E
Frog
Xenopus laevis
NP_001085915
682
79226
Y260
S
D
F
G
T
Q
L
Y
E
Q
K
V
V
E
L
Zebra Danio
Brachydanio rerio
XP_694124
738
84421
Y304
C
E
P
G
T
Q
N
Y
E
Q
W
V
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176480
823
93488
V302
Q
I
Y
E
Q
G
V
V
K
L
E
E
K
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.8
84.6
N.A.
78.9
79.1
N.A.
26.9
23.7
51.1
38.8
N.A.
N.A.
N.A.
N.A.
28.6
Protein Similarity:
100
99.4
97.9
91.4
N.A.
87.6
87.7
N.A.
43.9
35.8
67.4
57.1
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
93.3
93.3
80
N.A.
80
80
N.A.
6.6
46.6
66.6
53.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
100
100
N.A.
13.3
73.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
10
0
0
0
0
82
0
10
10
0
19
10
% E
% Phe:
0
0
73
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
82
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
10
0
0
10
0
0
0
0
10
19
0
% I
% Lys:
0
10
0
0
0
0
10
0
10
10
10
0
10
28
10
% K
% Leu:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
64
% L
% Met:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
28
19
0
0
10
91
0
0
0
82
55
0
10
28
10
% Q
% Arg:
37
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
19
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
73
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
10
0
0
10
82
73
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _